Variasi Dosis Spray Ekstrak Etanol Solanum melongena L. dan Cananga adorata terhadap Perubahan Gejala Toksik, Fungsi Hepar, dan Hispatologi Mencit (Mus musculus)

The purpose of this study was to determine toxic symptoms (loss reflex), enzyme activity SGOT and SGPT, liver histopathology experimental mice (Mus musculus) exposed a combination formulation 96% ethanol extract spray Solanum melongena L. Cananga adorata flower oil. True research design with Post Test Only Control Group Design, used 4 treatment groups 1 control group, data collected in the form enzymatic activity, histopathological picture musculus). Which analyzed by One Way Anova Descriptive test. results showed that changes physical reflexes) after 30 minutes spraying were strange reactions walking around without direction, sensitivity touch, social interaction colliding each other, lethargy, eye opacity excessive blinking, respiratory rate. increased, which returned normal at hours 168 spraying. SGPT enzymes higher dosage formulation, enzymes, but increase still within limits, morphology grading various doses Normal Mild. Conclusion: oil combined did not cause pathological effects